Schizophrenia and Neurotransmitters
Title: Schizophrenia and Neurotransmitters by
Name: Ms Videsha Bansal Email Id: bansal.videsha@gmail.com Current Designation: Research Assistant Chatterjee's NeuroImaging and AI Lab Address: Tongmyong University, Busan, South Korea LinkedIn Page: https://www.linkedin.com/in/videshabansal001
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Abstract:
Schizophrenia, a complex psychological disorder, presents a diagnostic challenge due to its overlap in symptoms with psychosis, making it more difficult to discern compared to other psychological disorders. Affecting approximately 1 per cent of the global population, this disorder is characterized by disruptions in thought processes, perceptions, and emotions. The underlying cause of schizophrenia is attributed to a chemical imbalance in the brain, drawing attention to the pivotal role of neurotransmitters in its manifestation.
The intricate web of neurotransmitters, acting as messengers in the brain, governs various cognitive and emotional functions. Recognizing their involvement in schizophrenia, researchers have embarked on an extensive exploration of the nuanced interplay between neurotransmitters and the disorder. This paper undertakes a comprehensive critical review of existing literature that delves into the diverse neurotransmitters implicated in schizophrenia. By scrutinizing previous studies, the aim is to consolidate the current understanding and identify gaps in knowledge that warrant further investigation.
In the subsequent phase, the paper meticulously identifies and elaborates on the most significant neurotransmitters associated with schizophrenia. Dopamine, glutamate, GABA, serotonin, and oxytocin emerge as key players in the intricate neural landscape of the disorder. Among these, dopamine stands out as the predominant contributor to the manifestation of schizophrenia. The paper delves into an in-depth exploration of the functional roles and effects of these neurotransmitters, shedding light on the complex mechanisms that underlie the disorder.
This study not only provides a comprehensive overview of the existing literature but also contributes novel insights by encapsulating all known neurotransmitters, enzymes, and chemicals associated with schizophrenia for the first time. The synthesis of this information enables a more holistic understanding of the neurochemical basis of the disorder. By identifying gaps and unexplored research questions, the paper lays the groundwork for future investigations to unravel the intricacies of neurotransmitter involvement in schizophrenia.
Furthermore, the research community's unsolved problems are brought to the forefront, emphasizing the need for continued exploration and inquiry into the intricate dynamics of neurotransmitters in schizophrenia. This paper serves as a cornerstone for future research endeavours, providing a roadmap for unravelling the complexities of neurochemical contributions to the disorder and offering valuable insights for the development of targeted interventions and treatments.
Keywords: Schizophrenia, neurotransmitters, dopamine, serotonin, symptoms
Biography:
Videsha Bansal is a chemical engineer turned full-time neuroscience researcher. She has been working in the field of schizophrenia and neurotransmitters. She has a total of 3 years of experience including research work in the field of neuroscience, paper publication and teaching. She has several SCI Scopus papers in the field of neuroscience (schizophrenia). She is a research assistant at Chatterjee’s NeuroImaging and AI Lab, Tongmyong University, Busan, South Korea.
