Head and Neck Lymphatic Obstruction and Dysphagia Following Chemo-radiotherapy for Head and Neck...
- OLCIAS
- Jun 12, 2023
- 2 min read
Updated: Jun 20, 2023
Title Talk: Head and Neck Lymphatic Obstruction and Dysphagia Following Chemo-radiotherapy for Head and Neck Cancer : A Retrospective, Linear, and Experimental Research
Author: Dr.Tshetiz Dahal (MBBS)
General Physician/Clinical Researcher and Writer
Lugansk State Medical University, Luhansk Oblast, Luhansk,
Ukraine
China Three Gorges University, Yichang, Hubei Province,
P. R. China
Email: dahaltshetiz21@gmail.com
ORCID ID : https://orcid.org/0000-0002-4042-7768
Volume: Brain 2023_CN37_AA04
International Live Conference on Brain: Latest Discoveries and Inventions Date: June16, 2023
Time:8 PM Indian Standard Time
Location: Online Conference
Theme: Unlocking the Mysteries of the Brain: Advancements, Innovations, and Impact
Abstract:
The study's objectives were to investigate (a) the development of external and internal head and neck lymphoedema (HNL) in head and neck cancer (HNC) patients up to 12 months after chemo-radiotherapy (CRT), and (b) the association between HNL and swallowing performance. External/internal HNL and swallowing were assessed in 33 patients using a prospective longitudinal cohort study at 3, 6, and 12 months after CRT. Using the MD Anderson Cancer Center Lymphoedema Rating Scale and the Assessment of Lymphoedema of the Head and Neck, external HNL was evaluated. Using Patterson's Radiotherapy Oedema Rating Scale, internal HNL was evaluated. Clinical, instrumental, and patient-reported assessments were used to evaluate swallowing. Multi-variable regression models were used to evaluate the relationships between HNL and swallowing. External HNL was prevalent at 3 months (71%), improved by 6 months (58%) and largely resolved by 12 months (10%). In contrast, moderate/severe internal HNL was prevalent at 3 months (96%), 6 months (84%) and at 12 months (65%). More severe penetration/aspiration and increased diet modification were associated with higher severities of external HNL (p=0.006 and p=0.031, respectively) and internal HNL (p<0.001 and p=0.007, respectively), and more diffuse internal HNL (p=0.043 and p=0.001, respectively). Worse patient- reported swallowing outcomes were associated with a higher severity of external HNL (p=0.001) and more diffuse internal HNL (p=0.002). External HNL largely resolves by 12 months post CRT, but internal HNL persists. Patients with a higher severity of external and/or internal HNL and those with more diffuse internal HNL can be expected to have more severe dysphagia.
